WebApr 16, 2024 · Hypertrophic cardiomyopathy (HCM) is often seen in patients as an autosomal dominant genetic heart disease with a variable clinical course. It is characterized by left ventricular hypertrophy, and... WebPipeline - Cytokinetics A pipeline powered by passion pipeline Research Pre-Clinical Phase 1 Phase 2 Phase 3 CARDIAC MUSCLE Omecamtiv Mecarbil (Heart Failure) Aficamten (oHCM) Aficamten (nHCM) CK-136 (Heart Failure, other) CK-586 SKELETAL … Cytokinetics is developing reldesemtiv, a fast skeletal muscle troponin activator …
nHCM and HFpEF Overlap: An Opportunity or a Trap?
WebMay 3, 2024 · Disclosures. Masri has received research grants from Pfizer, Ionis, Akcea, Ultromics and the Wheeler Foundation, fees (honoraria or consulting) from Eidos, Pfizer, Ionis, Alnylam, Cytokinetics, Bristol Meier Squibb, Tenaya, and Attralus, and served or currently serving as PI on EXPLORER‐HCM, PIONEER‐OLE, MAVA‐LTE, VALOR‐HCM, … WebMar 4, 2024 · Cytokinetics is a late-stage biopharmaceutical company focused on discovering, developing and commercializing first-in-class muscle activators and next-in-class muscle inhibitors as potential treatments for debilitating diseases in which muscle performance is compromised. chirality in hindi
Cytokinetics Announces Positive Topline Results of …
WebFeb 25, 2024 · Aficamten is under development for the treatment of obstructive hypertrophic cardiomyopathy (oHCM), non-obstructive hypertrophic cardiomyopathy (nHCM), heart failure with reserved ejection fraction (HFpEF). It is a new molecular entity administered through oral route. The drug candidates are cardiac muscle activators which act by … WebSep 13, 2024 · Cytokinetics recently announced the full results of its REDWOOD-HCM phase 2 clinical trial of aficamten in subjects with hypertrophic cardiomyopathy (HCM), along with additional results from its GALACTIC-HF study. The trials were designed to measure the effects of omecamtiv mecarbil in black patients with heart failure (HF) with reduced ... WebDec 9, 2024 · Cytokinetics is also developing CK-274, a next-generation cardiac myosin inhibitor, for the potential treatment of hypertrophic cardiomyopathies (HCM). … chirality in light–matter interaction