WebSep 1, 2003 · Cytolytic responses to anti-KIR mAbs in polyclonal NK cell lines from LDGL patients. Seven NKLGL cell lines derived from the indicated patients and 2 controls were analyzed for cytolytic responses in a redirected killing assay either in the absence or in the presence of different mAbs: EB6 (a), GL183 (b), FES172 (c), Z27 (d), or anti-CD16 (e). WebMay 16, 2001 · To this aim, cytolytic assays using NK cell clones and autologous APC as target cells were performed in the absence or in the presence of anti-NKp30 or anti-NKp44 or anti-NKp46 mAb alone or in combination. As shown in Fig. 4 (A and B), the addition of anti-NKp30 or anti-NKp46 mAb to the cytolytic assay consistently reduced, by …
ArsenalBio Announces Presentation of Six Abstracts at AACR …
WebMay 18, 2006 · Cytolytic activity of healthy donor CD8 T cells stimulated with individual or a combination of HER2/neu peptides. DC and CD8 T cells were purified from 6 HLA-A2 + healthy donor PBMC samples. CD8 T cells were stimulated once with GP2 or E75 peptide-loaded autologous DC and then utilized in standard 4-hour chromium-release assays … WebJul 29, 2010 · A simple and sensitive method to measure their activity would greatly benefit basic and clinical studies. For a long time, chromium ( 51 Cr) release assay has … chinese elephant live stream
Multiplex Screening Assay for Identifying Cytotoxic …
WebNov 30, 2010 · To evaluate the contribution of one or another activating NK receptor in killing of macrophages, cytolytic assays were performed in the presence of mAbs specific for major activating NK receptors. As shown in Fig. 1C, NKp46 and DNAM-1 mainly contributed to the lysis of macrophages. Indeed, mAb-mediated disruption of their … WebApr 14, 2024 · The best-performing candidates were shown to be superior to CAR T cells in a long-term killing assay, showed potent cytotoxicity of low expressing antigen lines, and displayed background levels of ... WebDec 31, 2005 · The chromium release microcytotoxicity assay (CRA) is the standard and most frequently used assay for assessment of cell-mediated cytotoxicity in vitro. … grand haven recycle center