Nephrotoxic effects
Web例文 These compounds are known for their nephrotoxic and carcinogenic effects. これらの化合物は、腎毒性および発がん作用で知られています。 例文 High concentration of streptomycin could lead to ototoxic and nephrotoxic effects. WebNov 7, 2014 · Novel associations and descriptions of nephrotoxic effects of common and emerging drugs of abuse have appeared over the past several years. Anabolic …
Nephrotoxic effects
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WebThe incidence of nephropathy induced by low-osmolar contrast medium is low in the general population and has been calculated to be less than 2 percent. 3 Patients at increased … WebIntroduction. Homeostasis of many physiological parameters depends, to a substantial degree, on vital functions of the renal system. 1 Indeed, a lot of therapeutic and diagnostic substances can induce considerable nephrotoxic effects that could progress to acute kidney injury (AKI) and advanced state of chronic kidney disease (CKD), particularly …
WebMar 22, 2024 · They exert their main toxic effect within the tubular cell by altering phospholipid metabolism. In addition to their direct effect on cells, aminoglycosides cause renal vasoconstriction. The 2 critical factors in the development of acute kidney injury (AKI) secondary to aminoglycoside nephrotoxicity are dosing and duration of therapy. WebDrugs eliminated via the kidneys can accumulate during acute kidney injury (AKI) or chronic kidney disease (CKD) and this can lead to further renal impairment or adverse effects. A review of these drugs is therefore required; any drug which can cause or exacerbate renal impairment should be avoided in AKI, and the appropriateness reviewed in CKD.
WebOct 6, 2016 · Cisplatin [Cis-diamminedichloroplatinum(II)] is the most nephrotoxic chemotherapeutic drug, discovered over four decades ago. Nephrotoxicity is the major side effect that limits the dose of cisplatin that can be safely administered, and it is a clinical problem in cancer patients who receive cisplatin combination chemotherapy. WebMay 18, 2024 · Impaired kidney function is a relatively common complication of amphotericin B, as are other kidney manifestations, including urinary potassium wasting and …
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WebThe most common nephrotoxic effects associated with HAART include crystal-induced obstruction secondary to use of protease inhibitors (mainly indinavir and atazanavir), and … how does someone become an inventorWebThe intensifying world-wide spread of mycotoxigenic fungal species has increased the possibility of mycotoxin contamination in animal feed and the human food chain. Growing evidence shows the deleterious toxicological effects of mycotoxins from infants to adults, while large population-based screening programs are often missing to identify affected … how does someone become blindWebDrugs cause approximately 20 percent of community-and hospital-acquired episodes of acute renal failure. 1 – 3 Among older adults, the incidence of drug-induced … how does someone become catholicWebTherefore, the present study was aimed at evaluating the nephrotoxic effects of diazinon and its mechanism of action with special reference to its possible ROS generating potential in rats. Treatment of rats with diazinon significantly enhances renal lipid peroxidation which is accompanied by a decrease in the activities of renal antioxidant ... how does someone become radicalisedWebMale mice appear to be more susceptible than female mice to the acute nephrotoxic effects of inhaled 1,1-dichloroethene and more susceptible than both sexes of rats. Acute-duration inhalation and oral studies have demonstrated that fasted animals are more susceptible than nonfasted animals to 1,1-dichloroethene renal toxicity. Developmental ... how does someone become homelessWebAug 1, 2024 · Nephrotoxicity can be defined as the adverse effect of substances on renal function (Perazella, 2009).These substances can include molds and fungi, cancer … photo size reformer for large postersWebThese side effects correlate with the high plasma concentration of tenofovir achieved by TDF. Due to raising safety concerns, TAF was developed as a safer alternative given its comparable efficacy but significant low dose requirement. Preclinical and clinical studies showed lower nephrotoxic potential of TAF compared with TDF. photo sizing for printing